Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15458790 | 0.82 | CYP11B1 (0.57) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL6774868 | 0.80 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL9092542 | 0.79 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27388451 | 0.79 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27316522 | 0.74 | CYP11B1 (0.60) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL1757759 | 0.74 | CYP11B1 (0.66) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL9092959 | 0.74 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27306308 | 0.73 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL10790711 | 0.73 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL12794259 | 0.73 | HSP90AA1 (0.55) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068592-C | Imidazole derivatives having affinity for alpha 2 receptors activity | ORION YHTYMAE OY (FI) | 2001-07-18 | — | — | CN | disclosed |
| CN-1198741-A | Imidazole derivatives having affinity for alpha 2 receptor activity | ORION YHTYMAE OY (FI) | 1998-11-11 | — | — | CN | disclosed |