Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9092542 | 0.82 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27388451 | 0.79 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL8249323 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL6774868 | 0.77 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27306308 | 0.77 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL15458790 | 0.77 | CYP11B1 (0.57) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL9531170 | 0.76 | GPBAR1 (0.41) | CYP11B1CYP11B2GAAGPBAR1 | |
| SCHEMBL27316522 | 0.75 | CYP11B1 (0.60) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL10790711 | 0.74 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL7041449 | 0.74 | CYP11B1 (0.51) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559141-A | TREATMENT OF BREAST CANCER AND BENIGN PROSTATE HYPERPLASIA | ORION-YHTYMA OY (FI) | 1996-09-24 | — | — | US | disclosed |
| EP-0589975-A1 | NEW SELECTIVE AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992022537-A1 | NEW SELECTIVE AROMATASE INHIBITING 4(5)-IMIDAZOLES | Orion-Yhtymä Oy (FI) | 1992-12-23 | — | — | WO | disclosed |