Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786604 | 0.83 | KDM4E (0.70) | TSHRALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8784898 | 0.82 | CSF1R (0.62) | TSHRALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11375460 | 0.81 | ALDH1A1 (0.63) | TSHRALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL9363020 | 0.81 | TUBB4A (0.53) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL9359174 | 0.79 | TUBB4A (0.51) | TSHRALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL27396160 | 0.78 | RET (0.43) | TSHRKMT2ALMNASMN1; SMN2PADI4 | |
| SCHEMBL8786825 | 0.72 | MEN1 (0.54) | TSHRALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL4591940 | 0.72 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL9358956 | 0.72 | MEN1 (0.53) | TSHRALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL5331127 | 0.72 | KDM4E (0.58) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| CN-1090274-A | Condensed heterocyclic compounds and its preparation method and application | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-08-03 | — | — | CN | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |