Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.34 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927948 | 0.88 | PTGDR2 (0.39) | USP28USP25PDPK1HTTALDH1A1 | |
| SCHEMBL8359689 | 0.76 | CCR5 (0.31) | — | |
| SCHEMBL8356086 | 0.74 | NPC1 (0.41) | PDPK1ALDH1A1GAAHPGDPOLB | |
| SCHEMBL8358341 | 0.74 | SIGMAR1 (0.50) | HTTALDH1A1GAAPOLBMAPT | |
| SCHEMBL3846753 | 0.71 | NPC1 (0.38) | PDPK1ALDH1A1GAAHPGDPOLB | |
| SCHEMBL16229879 | 0.71 | ESR1 (0.49) | ALDH1A1GAAPOLBMAPTESR1 | |
| SCHEMBL4667993 | 0.71 | CYP1A2 (0.41) | HTTALDH1A1GAAHPGDPOLB | |
| SCHEMBL8359695 | 0.70 | LMNA (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL4904766 | 0.70 | CYP1A2 (0.40) | HTTALDH1A1GAAHPGDPOLB | |
| SCHEMBL27397367 | 0.69 | GSK3B (0.41) | ALDH1A1L3MBTL1GAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235871-B1 | Synthesis of oligoarylamines, and uses and reagents related thereto | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-22 | — | — | US | disclosed |
| WO-1999028290-A1 | SYNTHESIS OF OLIGOARYLAMINES, AND USES AND REAGENTS RELATED THERETO | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1999-06-10 | — | — | WO | disclosed |