Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 10/20 | 0.42 |
| ▸ | WEE1 | P30291 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905534 | 1.00 | PKMYT1 (0.42) | PKMYT1WEE1PARP1MKNK1MKNK2 | |
| SCHEMBL27400120 | 0.87 | PRMT5 (0.39) | PKMYT1WEE1PARP1MKNK1MKNK2 | |
| SCHEMBL27398651 | 0.86 | LCK (0.37) | PKMYT1WEE1PARP1MKNK1MKNK2 | |
| SCHEMBL27399247 | 0.85 | MKNK1 (0.50) | PARP1MKNK1MKNK2PRMT5LCK | |
| SCHEMBL27399916 | 0.85 | PRMT5 (0.38) | PKMYT1WEE1PARP1MKNK1MKNK2 | |
| SCHEMBL30905539 | 0.85 | IKBKB (0.41) | PKMYT1PARP1MKNK1MKNK2CYP3A4 | |
| SCHEMBL27397408 | 0.85 | IKBKB (0.41) | PKMYT1PARP1MKNK1MKNK2CYP3A4 | |
| SCHEMBL27399919 | 0.85 | MKNK1 (0.38) | PARP1MKNK1MKNK2PRMT5LCK | |
| SCHEMBL27400121 | 0.85 | PRMT5 (0.39) | PKMYT1WEE1PARP1MKNK1MKNK2 | |
| SCHEMBL30905608 | 0.85 | PKMYT1 (0.38) | PKMYT1WEE1PARP1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |