Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905539 | 1.00 | IKBKB (0.41) | IKBKBKDM4EALDH1A1PKMYT1ADORA2A | |
| SCHEMBL30905556 | 0.88 | TDP2 (0.39) | PKMYT1ADORA2AMAPTBRD4 | |
| SCHEMBL27398649 | 0.87 | MKNK1 (0.35) | IKBKBKDM4EALDH1A1PKMYT1ADORA2A | |
| SCHEMBL27401511 | 0.86 | IKBKB (0.42) | IKBKBKDM4EALDH1A1PKMYT1ADORA2A | |
| SCHEMBL30905596 | 0.86 | IKBKB (0.42) | IKBKBKDM4EALDH1A1PKMYT1ADORA2A | |
| SCHEMBL27401362 | 0.86 | PKMYT1 (0.44) | IKBKBKDM4EALDH1A1PKMYT1ADORA2A | |
| SCHEMBL27397409 | 0.85 | PKMYT1 (0.42) | KDM4EPKMYT1PARP1CYP3A4CYP2C9 | |
| SCHEMBL30905534 | 0.85 | PKMYT1 (0.42) | KDM4EPKMYT1PARP1CYP3A4CYP2C9 | |
| SCHEMBL27399247 | 0.83 | MKNK1 (0.50) | IKBKBKDM4EALDH1A1PARP1LMNA | |
| SCHEMBL27399919 | 0.83 | MKNK1 (0.38) | ADORA2AADORA1PARP1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622967-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |