Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 10/20 | 0.36 |
| ▸ | WEE1 | P30291 | 3/20 | 0.36 |
| ▸ | EPHB3 | P54753 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905534 | 0.85 | PKMYT1 (0.42) | PRMT5PKMYT1WEE1EPHB3CYP3A4 | |
| SCHEMBL27397409 | 0.85 | PKMYT1 (0.42) | PRMT5PKMYT1WEE1EPHB3CYP3A4 | |
| SCHEMBL30905573 | 0.84 | PKMYT1 (0.42) | PRMT5LMNAPKMYT1WEE1EPHB3 | |
| SCHEMBL27397362 | 0.84 | PKMYT1 (0.42) | PRMT5LMNAPKMYT1WEE1EPHB3 | |
| SCHEMBL27399247 | 0.82 | MKNK1 (0.50) | PRMT5LMNAPARP1MKNK1MKNK2 | |
| SCHEMBL27400120 | 0.82 | PRMT5 (0.39) | PRMT5LMNAPKMYT1WEE1PARP1 | |
| SCHEMBL27399933 | 0.81 | PRMT5 (0.41) | PRMT5LMNAPARP1MKNK1MKNK2 | |
| SCHEMBL27398651 | 0.81 | LCK (0.37) | PRMT5LMNAPKMYT1WEE1EPHB3 | |
| SCHEMBL27399014 | 0.81 | LCK (0.51) | PRMT5LMNAPARP1MKNK1MKNK2 | |
| SCHEMBL30905539 | 0.80 | IKBKB (0.41) | LMNAPKMYT1CYP3A4CYP2C9PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |