Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802884 | 0.87 | CA2 (0.42) | CYP2C9CYP2C19GAAKDM4EMAPT | |
| SCHEMBL8804253 | 0.80 | CDK1 (0.51) | ALDH1A1GAAKDM4EMAPTNPC1 | |
| SCHEMBL8806828 | 0.78 | CA12 (0.38) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL8661923 | 0.74 | CDK1 (0.43) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9201412 | 0.74 | CDK1 (0.43) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7953153 | 0.73 | CA1 (0.43) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7924986 | 0.71 | LMNA (0.45) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL8661476 | 0.71 | CDK1 (0.45) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7876015 | 0.71 | HPGD (0.53) | ALDH1A1CYP2C9CYP2C19CYP3A4GAA | |
| SCHEMBL7876018 | 0.71 | HPGD (0.53) | ALDH1A1CYP2C9CYP2C19CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723409-A | Intermediates for the preparation of phenylsulfonylurea herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0666852-B1 | NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5449812-A | Substituted benzenesulfonamide derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-12 | — | — | US | disclosed |
| EP-0666852-A1 | NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS. | HOECHST SCHERING AGREVO GMBH (DE) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994010154-A1 | NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1994-05-11 | — | — | WO | disclosed |