Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815331 | 0.88 | MAPT (0.48) | MAPTTP53IGF1RDRD2KMT2A | |
| SCHEMBL27398013 | 0.87 | HTR1A (0.48) | DRD2HTR2AHRH1KMT2AHTR1A | |
| SCHEMBL13419252 | 0.86 | MAPT (0.52) | MAPTTP53IGF1RDRD2HTR2A | |
| SCHEMBL13419227 | 0.80 | MAPT (0.53) | MAPTTP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13419225 | 0.77 | KCNH2 (0.44) | MAPTTP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20363922 | 0.77 | SLC6A2 (0.46) | MAPTTP53DRD2HTR2AKMT2A | |
| SCHEMBL13419336 | 0.75 | MAPT (0.50) | MAPTTP53KMT2AHTR1AADRA1B | |
| SCHEMBL15759190 | 0.75 | DRD2 (0.45) | DRD2DRD4 | |
| SCHEMBL12082239 | 0.75 | ALDH1A1 (0.54) | MAPTTP53KMT2AHTR1AADRA1B | |
| SCHEMBL12082405 | 0.75 | ALDH1A1 (0.53) | MAPTKMT2AHTR1AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050370-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-03-07 | — | — | WO | disclosed |