Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399003 | 0.84 | LMNA (0.39) | LMNAL3MBTL1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27398995 | 0.82 | RXFP1 (0.40) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL27398984 | 0.82 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNANPC1KMT2A | |
| SCHEMBL27399789 | 0.74 | DGAT1 (0.41) | SMN1; SMN2 | |
| SCHEMBL31051183 | 0.73 | CYP1A2 (0.35) | ALDH1A1NPC1KMT2AGAAPOLB | |
| SCHEMBL27399009 | 0.73 | CYP1A2 (0.35) | ALDH1A1NPC1KMT2AGAAPOLB | |
| SCHEMBL27399110 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1LMNAOGG1NPC1 | |
| SCHEMBL31083590 | 0.72 | SCN10A (0.30) | — | |
| SCHEMBL31083490 | 0.72 | NPC1 (0.37) | KDM4ENPC1KMT2APOLBL3MBTL1 | |
| SCHEMBL27399729 | 0.72 | L3MBTL1 (0.37) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126404-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |