Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 14/20 | 0.42 |
| ▸ | WEE1 | P30291 | 2/20 | 0.42 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.37 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397362 | 1.00 | PKMYT1 (0.42) | PKMYT1WEE1EPHB3PRMT5LMNA | |
| SCHEMBL27399927 | 0.86 | LIMK1 (0.37) | PKMYT1WEE1EPHB3PRMT5LMNA | |
| SCHEMBL27401362 | 0.85 | PKMYT1 (0.44) | PKMYT1PRMT5LMNAKDM4EPARP1 | |
| SCHEMBL27397409 | 0.85 | PKMYT1 (0.42) | PKMYT1WEE1EPHB3PRMT5CYP3A4 | |
| SCHEMBL30905534 | 0.85 | PKMYT1 (0.42) | PKMYT1WEE1EPHB3PRMT5CYP3A4 | |
| SCHEMBL27400121 | 0.84 | PRMT5 (0.39) | PKMYT1WEE1EPHB3PRMT5LMNA | |
| SCHEMBL27398305 | 0.83 | PKMYT1 (0.45) | PKMYT1WEE1EPHB3LMNACYP3A4 | |
| SCHEMBL30905521 | 0.83 | PKMYT1 (0.45) | PKMYT1WEE1EPHB3LMNACYP3A4 | |
| SCHEMBL30905495 | 0.81 | PKMYT1 (0.44) | PKMYT1WEE1EPHB3KDM4EIL1B | |
| SCHEMBL30905494 | 0.81 | PKMYT1 (0.44) | PKMYT1WEE1EPHB3KDM4EIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622967-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |