Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399335 | 0.85 | PRMT5 (0.39) | KDM4EPRMT5LCKBTKCCNC | |
| SCHEMBL27400870 | 0.82 | SYK (0.36) | KDM4EPRMT5LCKBTKCCNC | |
| SCHEMBL27399247 | 0.81 | MKNK1 (0.50) | KDM4EALDH1A1PRMT5LCKBTK | |
| SCHEMBL27399933 | 0.81 | PRMT5 (0.41) | KDM4EALDH1A1PRMT5LCKBTK | |
| SCHEMBL27399014 | 0.80 | LCK (0.51) | PRMT5LCKBTKPARP1MKNK1 | |
| SCHEMBL27399603 | 0.79 | MKNK1 (0.40) | KDM4EALDH1A1PRMT5LCKBTK | |
| SCHEMBL27400752 | 0.78 | DYRK1A (0.38) | KDM4EALDH1A1PARP1LIMK1EGFR | |
| SCHEMBL27398651 | 0.78 | LCK (0.37) | KDM4EPRMT5LCKBTKPARP1 | |
| SCHEMBL30905534 | 0.77 | PKMYT1 (0.42) | KDM4EPRMT5LCKBTKPARP1 | |
| SCHEMBL27397409 | 0.77 | PKMYT1 (0.42) | KDM4EPRMT5LCKBTKPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |