Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAD | P27708 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27400849 | 1.00 | CAD (0.38) | CADL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7395542 | 0.86 | ITGB3 (0.34) | KMT2ASMN1; SMN2 | |
| SCHEMBL27400841 | 0.85 | GAA (0.45) | CADL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21282543 | 0.85 | GAA (0.45) | CADL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27400834 | 0.85 | GAA (0.45) | CADL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27400836 | 0.82 | L3MBTL1 (0.46) | CADL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27400838 | 0.82 | L3MBTL1 (0.46) | CADL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13863588 | 0.81 | ITGA4 (0.35) | CYP1A2CYP2C9CYP2C19HTTKMT2A | |
| SCHEMBL22316554 | 0.81 | L3MBTL1 (0.38) | CADL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL21906213 | 0.80 | ITGA4 (0.35) | CYP1A2CYP2C9CYP2C19HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | Sumitomo Pharma Co., Ltd. (JP) | 2024-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | FCGRT, QARS1, INHA | CAD 3674/4885L3MBTL1 4119/4885CYP1A2 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.