Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27401986 | 1.00 | GABRG2 (0.42) | GABRG2GABRB3GABRA2MAPTMEN1 | |
| SCHEMBL27402009 | 0.88 | GRM2 (0.43) | GABRG2GABRB3GABRA2MAPTMEN1 | |
| SCHEMBL30905535 | 0.88 | GRM2 (0.43) | GABRG2GABRB3GABRA2MAPTMEN1 | |
| SCHEMBL30905556 | 0.82 | TDP2 (0.39) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30905520 | 0.77 | CACNB4 (0.40) | MAPTMEN1KMT2AALDH1A1CACNB4 | |
| SCHEMBL27401510 | 0.77 | CACNB4 (0.40) | MAPTMEN1KMT2AALDH1A1CACNB4 | |
| SCHEMBL30905584 | 0.76 | KMT2A (0.46) | MAPTMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL27401713 | 0.76 | KMT2A (0.46) | MAPTMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL27402006 | 0.75 | KDM4E (0.45) | MAPTKMT2ATP53ALDH1A1ELANE | |
| SCHEMBL30905481 | 0.73 | GRM2 (0.46) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622967-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |