Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1A | O00555 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27403172 | 0.85 | OPRD1 (0.45) | CACNA1ACACNA2D1CACNB1CACNA1CPIK3CD | |
| SCHEMBL27403138 | 0.84 | CACNA1A (0.49) | CACNA1ACACNA2D1CACNB1CACNA1CPIK3CD | |
| SCHEMBL27403084 | 0.83 | CACNA1A (0.58) | CACNA1ACACNA2D1CACNB1CACNA1CPIK3CD | |
| SCHEMBL27411313 | 0.82 | PIK3CD (0.43) | CACNA1ACACNA2D1CACNB1CACNA1CPIK3CD | |
| SCHEMBL27403209 | 0.82 | CACNA1A (0.37) | CACNA1ACACNA2D1CACNB1CACNA1CPIK3CD | |
| SCHEMBL27411322 | 0.80 | OPRM1 (0.42) | NAMPTLMNASLC6A9ALDH1A1OPRM1 | |
| SCHEMBL27403139 | 0.79 | MGLL (0.43) | CACNA1ACACNA2D1CACNB1CACNA1CPIK3CD | |
| SCHEMBL27411475 | 0.79 | NAMPT (0.40) | CACNA1ACACNA2D1CACNB1CACNA1CPIK3CD | |
| SCHEMBL27403135 | 0.78 | CACNA1A (0.49) | CACNA1ACACNA2D1CACNB1CACNA1CPIK3CD | |
| SCHEMBL5193664 | 0.74 | CHRNA7 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024124287-A1 | COMPOUNDS FOR TREATING VIRAL INFECTION | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2024-06-20 | — | — | WO | disclosed |