Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 6/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720444 | 0.78 | ALDH1A1 (0.53) | DRD2DRD3ALDH1A1TP53CYP3A4 | |
| SCHEMBL27406469 | 0.78 | NOTUM (0.39) | DRD2DRD3KCNH2NOTUMESR1 | |
| SCHEMBL26607916 | 0.77 | AR (0.43) | DRD2DRD3KCNH2GRIN1GRIN2B | |
| SCHEMBL14349225 | 0.75 | NOTUM (0.54) | DRD2DRD3KCNH2NOTUMHPGD | |
| SCHEMBL3534359 | 0.75 | NOTUM (0.54) | DRD2DRD3KCNH2NOTUMHPGD | |
| SCHEMBL4547919 | 0.74 | NOTUM (0.52) | NOTUMHPGDLPAR5HRH3KDM4E | |
| SCHEMBL27405104 | 0.73 | NOTUM (0.49) | DRD2DRD3KCNH2NOTUMHPGD | |
| SCHEMBL19701949 | 0.72 | PIK3CD (0.47) | NOTUMESR1HPGDADAM10ALDH1A1 | |
| SCHEMBL19701973 | 0.72 | PIK3CD (0.39) | DRD2DRD3KCNH2NOTUMESR1 | |
| SCHEMBL27405147 | 0.72 | NOTUM (0.48) | NOTUMHPGDHRH3ADAM10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | ITGB1, ITGA1, ITGAV | DRD2 2698/4885DRD3 3031/4885KCNH2 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.