Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 15/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 11/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242174 | 0.84 | ADORA2A (0.56) | ADKMEN1PRMT5WDR77 | |
| SCHEMBL16254729 | 0.80 | METTL3 (0.53) | ADKMEN1PRMT5WDR77 | |
| SCHEMBL16236292 | 0.80 | MEN1 (0.50) | ADKMEN1PRMT5WDR77 | |
| SCHEMBL18727734 | 0.80 | ADK (0.48) | ADKPRMT5WDR77 | |
| SCHEMBL13314384 | 0.79 | ADK (0.53) | ADKMEN1PRMT5WDR77 | |
| SCHEMBL14447403 | 0.78 | MEN1 (0.43) | ADKMEN1PRMT5WDR77 | |
| SCHEMBL25047848 | 0.76 | ADK (0.50) | ADKMEN1PRMT5WDR77 | |
| SCHEMBL10293819 | 0.76 | MEN1 (0.47) | ADKMEN1PRMT5WDR77 | |
| SCHEMBL17830246 | 0.76 | MEN1 (0.49) | ADKMEN1PRMT5WDR77 | |
| SCHEMBL18484812 | 0.75 | PRMT5 (0.38) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402334-A1 | Inhibitors of E1 Activating Enzymes | Millennium Pharmaceuticals, Inc. (US) | 2012-01-04 | — | — | EP | disclosed |