Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4556847 | 0.86 | KIF11 (0.35) | RAB9APARP1MAOB | |
| Hydrochloric Acid SCHEMBL27513160 | 0.82 | FYN (0.35) | ADORA1NPC1RAB9AMAOBHSD17B10 | |
| Hydrochloric Acid SCHEMBL16394004 | 0.81 | RXRB (0.33) | — | |
| SCHEMBL1454517 | 0.81 | BRD4 (0.40) | HTR1AHTR7KDM1ARORCRORB | |
| Hydrochloric Acid SCHEMBL29424591 | 0.80 | PDCD1 (0.35) | HTR1AHTR7BRD4ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3163965 | 0.80 | PDCD1 (0.35) | HTR1AHTR7BRD4ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5709184 | 0.80 | PDCD1 (0.35) | HTR1AHTR7BRD4ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7932490 | 0.80 | ESR2 (0.39) | HTR1AHTR7ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL8464927 | 0.79 | KDM1A (0.37) | HTR1AHTR7KDM1ARORCRORB | |
| Hydrochloric Acid SCHEMBL8461602 | 0.79 | HTR1A (0.38) | HTR1AHTR7KDM1ARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105672-A | Novel transition metal compound, olefin polymerization catalyst component comprising the transition metal compound, olefin polymerization catalyst comprising the olefin polymerization catalyst comp... | MITSUI PETROCHEMICAL IND (JP) | 1995-07-26 | — | — | CN | disclosed |