Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406259 | 0.90 | ALDH1A1 (0.47) | TAS1R3TAS1R1ALDH1A1MAPT | |
| SCHEMBL27461090 | 0.87 | TAS1R3 (0.43) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27384468 | 0.84 | KMT2A (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27406969 | 0.84 | TAS1R3 (0.62) | TAS1R3TAS1R1 | |
| SCHEMBL27405552 | 0.83 | TAS1R3 (0.47) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL9594891 | 0.82 | TAS1R3 (0.49) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL8744837 | 0.82 | TAS1R3 (0.49) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL7950138 | 0.80 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL6993048 | 0.80 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL27386686 | 0.79 | ALDH1A1 (0.49) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075060-C | Alkoxy-alkyl-substd. 1-H-3-aryl-pyrrolidine-2,4-diones used as herbicides and pesticides | BAYER AG (DE) | 2001-11-21 | — | — | CN | disclosed |
| CN-1147249-A | Alkoxy-alkyl-substituted 1-H-3-aryl-pyrrolidine-2, 4-diones as herbicides and pesticides | BAYER AG (DE) | 1997-04-09 | — | — | CN | disclosed |