Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993048 | 1.00 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL9594891 | 0.91 | TAS1R3 (0.49) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL8744837 | 0.91 | TAS1R3 (0.49) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL7950079 | 0.90 | ALDH1A1 (0.45) | TAS1R3TAS1R1ALDH1A1LMNARXFP1 | |
| SCHEMBL6998473 | 0.90 | ALDH1A1 (0.45) | TAS1R3TAS1R1ALDH1A1LMNARXFP1 | |
| SCHEMBL7094315 | 0.90 | MAPK1 (0.44) | ALDH1A1THRBLMNARXFP1LPAR1 | |
| SCHEMBL7094314 | 0.90 | MAPK1 (0.44) | ALDH1A1THRBLMNARXFP1LPAR1 | |
| SCHEMBL7961970 | 0.87 | MEN1 (0.43) | TAS1R3TAS1R1LMNARXFP1LPAR1 | |
| SCHEMBL6990018 | 0.87 | MEN1 (0.43) | TAS1R3TAS1R1LMNARXFP1LPAR1 | |
| SCHEMBL7964617 | 0.84 | TAS1R3 (0.48) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |