Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22075818 | 0.74 | KDM4E (0.53) | TSHRGAAKDM4EHTTMEN1 | |
| SCHEMBL2945430 | 0.72 | TSHR (0.39) | TSHRGAAKDM4EHTTMEN1 | |
| SCHEMBL9322581 | 0.71 | TSHR (0.71) | TSHRGAAKDM4EALDH3A1MEN1 | |
| SCHEMBL18556696 | 0.70 | SMN1; SMN2 (0.49) | TSHRHTTALDH3A1L3MBTL1MEN1 | |
| SCHEMBL15929448 | 0.69 | KDM2B (0.46) | HTTPTGS2PTGS1LMNA | |
| Cyazofamid SCHEMBL16180421 | 0.68 | PTGS2 (0.38) | TSHRGAAKDM4EHTTL3MBTL1 | |
| Cyazofamid SCHEMBL22923 | 0.68 | PTGS2 (0.38) | TSHRGAAKDM4EHTTL3MBTL1 | |
| SCHEMBL23649472 | 0.67 | GAA (0.66) | TSHRGAAKDM4EHTTL3MBTL1 | |
| SCHEMBL28894077 | 0.67 | MAPT (0.40) | TSHRGAAHTTL3MBTL1MEN1 | |
| Cyazofamid SCHEMBL23804496 | 0.66 | PTGS2 (0.37) | TSHRGAAKDM4EHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1087292-C | Sulfonyloxadiazolones | BAYER AG (DE) | 2002-07-10 | — | — | CN | disclosed |