Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26562238 | 0.96 | PAX8 (0.38) | PAX8KMT2AMEN1USP2POLB | |
| SCHEMBL12211060 | 0.93 | PTPN1 (0.37) | PAX8PTPN1LMNATSHRPRKCA | |
| SCHEMBL25492659 | 0.92 | PAX8 (0.42) | PAX8KMT2AMEN1USP2POLB | |
| SCHEMBL17776090 | 0.89 | PTPN1 (0.39) | PTPN1LGALS3LGALS4 | |
| SCHEMBL17552001 | 0.89 | TSHR (0.48) | PAX8KMT2AMEN1USP2POLB | |
| SCHEMBL9604484 | 0.86 | LMNA (0.38) | PAX8KMT2AMEN1USP2POLB | |
| SCHEMBL15344765 | 0.85 | PAX8 (0.46) | PAX8KMT2AMEN1USP2POLB | |
| SCHEMBL19767541 | 0.85 | PAX8 (0.38) | PAX8KMT2AMEN1USP2POLB | |
| SCHEMBL4292941 | 0.85 | PTPN1 (0.48) | KMT2AMEN1USP2POLBPTPN1 | |
| SCHEMBL26491378 | 0.84 | LGALS3 (0.38) | PAX8KMT2AMEN1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209369-A1 | COMPLEMENT COMPONENT C3 IRNA COMPOSITIONS AND METHODS OF USE THEREOF | BANK OF AMERICA, N.A. | 2024-06-27 | — | — | US | disclosed |