Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | TYK2 | P29597 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588261 | 0.82 | CXCL8 (0.64) | SLC16A3KMT2AMEN1AKR1B10UGT1A9 | |
| SCHEMBL7395348 | 0.77 | GAA (0.46) | HTTSMN1; SMN2HPGDCYP1A2POLB | |
| SCHEMBL3714690 | 0.76 | PTGS2 (0.60) | KMT2ACYP3A4AKR1B10UGT1A9TRPA1 | |
| SCHEMBL28165041 | 0.76 | ALDH1A1 (0.52) | HTTSMN1; SMN2CYP3A4HPGDCYP1A2 | |
| SCHEMBL11207305 | 0.74 | HTT (0.63) | KMT2AMEN1HTTTAS1R3TAS1R1 | |
| SCHEMBL27602988 | 0.74 | KMT2A (0.55) | SLC16A3KMT2AMEN1CRHBPHTT | |
| SCHEMBL3552458 | 0.74 | SLC16A3 (1.00) | SLC16A3KMT2AMEN1HPGDCYP1A2 | |
| SCHEMBL11747275 | 0.74 | KMT2A (0.52) | SLC16A3KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11193641 | 0.73 | HDAC3 (0.49) | SMN1; SMN2HPGDPOLBGAAALDH1A1 | |
| SCHEMBL11751093 | 0.73 | NPC1 (0.63) | KMT2AMEN1SMN1; SMN2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047085-A | The dipeptides of renin-inhibiting, its preparation method contains the medicament and the application thereof of these dipeptides | HOECHST AG (DE) | 1990-11-21 | — | — | CN | claimed |
| CN-1047085-A | The dipeptides of renin-inhibiting, its preparation method contains the medicament and the application thereof of these dipeptides | HOECHST AG (DE) | 1990-11-21 | — | — | CN | disclosed |