Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 3/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.64 |
| ▸ | TTR | P02766 | 3/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.64 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.64 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.64 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.64 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27408685 | 0.82 | SLC16A3 (0.59) | CXCL8PTGS2TTRNR1H4AKR1B10 | |
| SCHEMBL21711305 | 0.79 | NR1H4 (0.75) | CXCL8PTGS2TTRNR1H4AKR1B10 | |
| SCHEMBL10445131 | 0.78 | BCAT2 (0.60) | CXCL8PTGS2TTRNR1H4AKR1B10 | |
| Diclofenac SCHEMBL2799 | 0.78 | PTGS2 (1.00) | CXCL8PTGS2TTRNR1H4AKR1B10 | |
| Diclofenac SCHEMBL996716 | 0.78 | PTGS2 (1.00) | CXCL8PTGS2TTRNR1H4AKR1B10 | |
| Diclofenac SCHEMBL29354260 | 0.78 | PTGS2 (1.00) | CXCL8PTGS2TTRNR1H4AKR1B10 | |
| SCHEMBL6537487 | 0.78 | TYK2 (0.49) | CXCL8PTGS2TTRNR1H4AKR1B10 | |
| SCHEMBL6243911 | 0.78 | CXCL8 (1.00) | CXCL8PTGS2TTRNR1H4AKR1B10 | |
| SCHEMBL3552458 | 0.77 | SLC16A3 (1.00) | SLC16A3KMT2AMEN1 | |
| SCHEMBL22981599 | 0.77 | PTGS2 (0.75) | CXCL8PTGS2TTRNR1H4AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100350905-C | Treatment of burns | NOVAR TIS CONSUMER HEALTH S A (CH) | 2007-11-28 | — | — | CN | disclosed |
| CN-1449282-A | Treatment of burns | NOVAR TIS CONSUMER HEALTH S A (CH) | 2003-10-15 | — | — | CN | disclosed |