Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27409003 | 0.83 | ADORA1 (0.35) | KDM4EL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL27408993 | 0.80 | MAPT (0.39) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14031549 | 0.75 | PDPK1 (0.40) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16741126 | 0.72 | TPH1 (0.40) | CCNCCDK8AAK1 | |
| SCHEMBL26260076 | 0.71 | HIF1A (0.41) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14951108 | 0.71 | TUBB4A (0.47) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30849054 | 0.70 | TUBB4A (0.34) | KDM4EL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL12924082 | 0.70 | LTA4H (0.42) | L3MBTL1LTA4HKMT2A | |
| SCHEMBL14535515 | 0.69 | CCR1 (0.54) | KDM4ELTA4HALDH1A1KMT2A | |
| SCHEMBL27895621 | 0.69 | TUBB4A (0.41) | KDM4ETUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024076891-A1 | POLO LIKE KINASE 4 INHIBITORS | ORIC PHARMACEUTICALS, INC. (US) | 2024-04-11 | — | — | WO | disclosed |