SCHEMBL561780

SCHEMBL561780

C=CCNC=C(C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 1/20 0.34
FAAH O00519 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 4/20 0.31
HPGD P15428 3/20 0.31
KDM4E B2RXH2 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
LMNA P02545 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821284 1.00 TSHR (0.34) TSHRSMN1; SMN2MAPTFAAHKMT2A
SCHEMBL6436298 0.81
SCHEMBL11963780 0.81 TSHR (0.35) TSHRSMN1; SMN2MAPTFAAHKMT2A
SCHEMBL589664 0.81 TSHR (0.35) TSHRSMN1; SMN2MAPTFAAHKMT2A
SCHEMBL5607925 0.79 ALDH1A1 (0.38) TSHRSMN1; SMN2MAPTFAAHKMT2A
SCHEMBL12006818 0.78 TSHR (0.31) TSHRSMN1; SMN2MAPTFAAH
SCHEMBL22818510 0.77 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL4792311 0.77 HTT (0.32) KMT2A
SCHEMBL368699 0.75 MAPT (0.35) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL9058790 0.75 ALDH1A1 (0.43) TSHRSMN1; SMN2MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395730-A1 DISSOLVABLE SOLID STRUCTURE COMPRISING FIRST AND SECOND POLYMERIC STRUCTURANTS The Procter & Gamble Company (US) 2024-07-10 EP claimed
US-11666514-B2 Fibrous structures containing polymer matrix particles with perfume ingredients THE PROCTER & GAMBLE COMPANY (US) 2023-06-06 US claimed
WO-2023034763-A1 DISSOLVABLE SOLID STRUCTURE COMPRISING FIRST AND SECOND POLYMERIC STRUCTURANTS THE PROCTER & GAMBLE COMPANY (US) 2023-03-09 WO claimed
US-20230060806-A1 DISSOLVABLE SOLID STRUCTURE COMPRISING FIRST AND SECOND POLYMERIC STRUCTURANTS THE PROCTER & GAMBLE COMPANY 2023-03-02 US claimed
CN-114599773-A Fabric care compositions with improved microbial robustness and methods of use thereof 高露洁-棕榄公司 2022-06-07 CN claimed
EP-3390483-B1 ENCAPSULATION PROCTER & GAMBLE (US) 2022-05-18 EP claimed
CN-107148267-B Active substance particles with dual taste masking technology, method for the production thereof and orodispersible tablets containing the same 埃迪制药公司 2021-03-12 CN claimed
US-20200093710-A1 FIBROUS STRUCTURES CONTAINING POLYMER MATRIX PARTICLES WITH PERFUME INGREDIENTS THE PROCTER & GAMBLE COMPANY 2020-03-26 US claimed
EP-0991368-B2 POLYMERIZABLE ISOLATION BARRIERS AND METHODS FOR FORMING AND USING SUCH BARRIERS ULTRADENT PRODUCTS INC (US) 2017-05-10 EP claimed
US-9192908-B2 Encapsulated solid hydrophilic particles ENCAPSYS, LLC (US) 2015-11-24 US claimed
EP-0906902-B1 A method for the production of an alkylamino (meth)acrylate and apparatus therefor. NIPPON CATALYTIC CHEM IND (JP) 2002-08-28 EP claimed
US-6417392-B1 CATALYTIC ESTER INTERCHANGE OF ALKYL (METH)ACRYLATE AND ALKYLAMINO ALCOHOL; DISTILLATION OF ALKYL ALCOHOL BY-PRODUCT IN AZEOTROPIC MIXTURE WITH ALKYL (METH)ACRYLATE; PURIFICATION USING ION EXCHANGE RESIN NIPPON SHOKUBAI CO., LTD. (JP) 2002-07-09 US claimed
US-6305936-B1 UNSATURATED MONOMER, CURING AGENT, WET TISSUE ADHERENCE ACCENTUATOR, REFLECTIVE MATERIAL AND ORGANIC POLYMERIZATION STRENGTH REDUCER; CONFINING DENTAL TREATMENT ULTRADENT PRODUCTS, INC. 2001-10-23 US claimed
US-6268528-B1 OXIDIZING DIALKYLNAPHTHALENE TO NAPHTHALENEDICARBOXYLIC ACID IN SOLVENT CONTAINING LOWER ALIPHATIC CARBOXYLIC ACID USING MOLECULAR OXYGEN-CONTAINING GAS IN PRESENCE OF A CATALYST COMPRISING COBALT COMPOUND, MANGANESE COMPOUND AND BROMINE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-07-31 US claimed
US-6086370-A Polymerizable isolation barriers containing reflective materials and methods for forming and using such barriers ULTRADENT PRODUCTS, INC. (US) 2000-07-11 US claimed
EP-0991368-A1 POLYMERIZABLE ISOLATION BARRIERS AND METHODS FOR FORMING AND USING SUCH BARRIERS Ultradent Products, Inc. (US) 2000-04-12 EP claimed
US-6048202-A THE POLYMERIZABLE ISOLATION BARRIER COMPRISING THE MIXTURE PRODUCTS OF ATLEAST ONE MONOMER, A CURING AGENT FOR CURING THE MONOMER AND A TISSUE ADHERENCE ACCENTUATOR SUCH AS GUM OR CELLULOSE PRODUCT ULTRADENT PRODUCTS, INC. (US) 2000-04-11 US claimed
EP-0982290-A2 Method for handling alkylamino (meth)acrylates Nippon Shokubai Co., Ltd. (JP) 2000-03-01 EP claimed
EP-0906902-A2 A method for the production of an alkylamino (meth)acrylate and apparatus therefor. NIPPON SHOKUBAI CO., LTD. (JP) 1999-04-07 EP claimed
WO-1998036700-A1 POLYMERIZABLE ISOLATION BARRIERS AND METHODS FOR FORMING AND USING SUCH BARRIERS ULTRADENT PRODUCTS, INC. (US) 1998-08-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11666514-B2 Fibrous structures containing polymer matrix particles with perfume ingredients FSCN1, FLNA, PFN1 TSHR 4800/4885SMN1; SMN2 3790/4885MAPT 61/4885
US-20200093710-A1 FIBROUS STRUCTURES CONTAINING POLYMER MATRIX PARTICLES WITH PERFUME INGREDIENTS FSCN1, FLNA, PFN1 TSHR 4800/4885SMN1; SMN2 3790/4885MAPT 61/4885
US-20230060806-A1 DISSOLVABLE SOLID STRUCTURE COMPRISING FIRST AND SECOND POLYMERIC STRUCTURANTS SGMS2, DEGS1, SGMS1 TSHR 3864/4885SMN1; SMN2 356/4885MAPT 1898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.