Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.60 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | IDH1 | O75874 | 3/20 | 0.50 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825507 | 0.81 | MCL1 (0.60) | CRHBPCRHR2NHERF1MCL1IDH1 | |
| SCHEMBL10825800 | 0.80 | CRHBP (0.65) | CRHBPCRHR2NHERF1MCL1IDH1 | |
| SCHEMBL10529391 | 0.78 | CRHBP (0.67) | CRHBPCRHR2NHERF1MCL1IDH1 | |
| SCHEMBL9515445 | 0.78 | CRHBP (0.74) | CRHBPCRHR2NHERF1MCL1NFKBIA | |
| SCHEMBL15821362 | 0.77 | L3MBTL1 (0.55) | CRHBPCRHR2NHERF1MCL1NFKBIA | |
| SCHEMBL3376788 | 0.77 | CRHBP (0.78) | CRHBPCRHR2NHERF1MCL1MEN1 | |
| SCHEMBL10529379 | 0.77 | CRHBP (0.82) | CRHBPCRHR2NFKBIARELAMEN1 | |
| SCHEMBL15647549 | 0.77 | NFKBIA (0.61) | CRHBPCRHR2NHERF1MCL1IDH1 | |
| SCHEMBL8309888 | 0.76 | CRHBP (1.00) | CRHBPCRHR2NHERF1SMN1; SMN2MEN1 | |
| SCHEMBL30680186 | 0.76 | CRHBP (0.67) | CRHBPCRHR2NHERF1MCL1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121399-C | Isothiazolcarboxylic acid derivatives | BAYER AG (DE) | 2003-09-17 | — | — | CN | disclosed |
| CN-1121401-C | aminophenol derivatives | BAYER AG (DE) | 2003-09-17 | — | — | CN | disclosed |
| CN-1101394-C | Sulfonyloxadiazolones and their use as microbicides | BAYER AG (DE) | 2003-02-12 | — | — | CN | disclosed |
| CN-1278804-A | Isothiazolecarboxylic acid derivatives | BAYER AG (DE) | 2001-01-03 | — | — | CN | disclosed |
| CN-1275980-A | Microbicide 1,4,2-dioxacine derivatives | BAYER AG (DE) | 2000-12-06 | — | — | CN | disclosed |
| CN-1252801-A | Sulfonyl oxadiazolones and their use as microbicides | BAYER AG (DE) | 2000-05-10 | — | — | CN | disclosed |
| CN-1240439-A | Aminophenol derivates with fungicidal property | BAYER AG (DE) | 2000-01-05 | — | — | CN | disclosed |