Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27461403 | 0.87 | FAAH (0.37) | TDP1FAAHPIK3CDCYP1A2PDE10A | |
| SCHEMBL27409940 | 0.87 | FAAH (0.36) | TDP1TP53MAPTHIF1AEPAS1 | |
| SCHEMBL27407936 | 0.87 | GHSR (0.36) | TDP1TP53MAPTGHSRHIF1A | |
| SCHEMBL27389952 | 0.86 | P2RX3 (0.35) | TDP1TP53MAPTALOX5AP | |
| SCHEMBL27413612 | 0.82 | TDP1 (0.34) | TDP1TP53MAPTPOLBTHRB | |
| SCHEMBL27397423 | 0.82 | TDP1 (0.37) | TDP1TP53MAPTPOLB | |
| SCHEMBL27409969 | 0.82 | TDP1 (0.35) | TDP1MAPT | |
| SCHEMBL27462484 | 0.82 | HDAC1 (0.35) | TDP1 | |
| SCHEMBL6966431 | 0.81 | TP53 (0.37) | TDP1TP53MAPTGHSRALOX5AP | |
| SCHEMBL27393362 | 0.81 | P2RX3 (0.37) | TDP1TP53MAPTPOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093535-C | Imidazole derivative | SHIONOGI & CO (JP) | 2002-10-30 | — | — | CN | disclosed |
| CN-1158609-A | Imidazole derivative | SHIONOGI & CO (JP) | 1997-09-03 | — | — | CN | disclosed |