SCHEMBL27410751 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	KDM4E	B2RXH2	3/20	0.40

▸	SIGMAR1	Q99720	2/20	0.37

▸	ATM	Q13315	2/20	0.36

▸	NPSR1	Q6W5P4	2/20	0.36

▸	MEN1	O00255	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	TDP1	Q9NUW8	1/20	0.36

▸	ALDH1A1	P00352	2/20	0.34

▸	KDM1A	O60341	1/20	0.34

▸	HSD11B1	P28845	2/20	0.33

▸	GAA	P10253	2/20	0.33

▸	GRIN1	Q05586	1/20	0.33

▸	GRIN2B	Q13224	1/20	0.33

▸	HTT	P42858	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19010252	1.00	KDM4E (0.40)	KDM4ESIGMAR1ATMNPSR1MEN1
SCHEMBL27410749	1.00	KDM4E (0.40)	KDM4ESIGMAR1ATMNPSR1MEN1
SCHEMBL19000029	0.83	KDM4E (0.42)	KDM4ESIGMAR1ATMNPSR1MEN1
SCHEMBL23866609	0.83	KDM4E (0.42)	KDM4ESIGMAR1ATMNPSR1MEN1
SCHEMBL23866597	0.83	KDM4E (0.42)	KDM4ESIGMAR1ATMNPSR1MEN1
SCHEMBL21661362	0.81	KDM4E (0.38)	KDM4ESIGMAR1ATMNPSR1MEN1
SCHEMBL19022016	0.80	SIGMAR1 (0.43)	KDM4ESIGMAR1ATMNPSR1MEN1
SCHEMBL15330120	0.80	SIGMAR1 (0.38)	KDM4ESIGMAR1ATMNPSR1MEN1
SCHEMBL19009039	0.80	PIK3CD (0.35)	KDM4EATM
SCHEMBL11293431	0.79	ATM (0.50)	KDM4ESIGMAR1ATMNPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024100139-A1	USE OF IFN-I ACTIVITY AS A BIOMARKER FOR TLR INHIBITOR TREATMENT	MERCK PATENT GMBH (DE)	2024-05-16	—	—	WO	disclosed