Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 7/20 | 0.57 |
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.56 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.49 |
| ▸ | PLD3 | Q8IV08 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16027839 | 0.91 | TRPC5 (0.67) | ALDH1A1TSHRKDM4EPOLBRAB9A | |
| SCHEMBL16028038 | 0.90 | RAB9A (0.57) | ALDH1A1TSHRKDM4EPOLBRAB9A | |
| SCHEMBL16363982 | 0.85 | TRPC5 (0.55) | ALDH1A1TSHRLMNATRPC5TRPC4 | |
| SCHEMBL16364033 | 0.84 | TSHR (0.69) | ALDH1A1TSHRKDM4EPOLBRAB9A | |
| SCHEMBL20432444 | 0.84 | TRPC5 (0.52) | ALDH1A1TSHRPOLBRAB9ALMNA | |
| SCHEMBL18833614 | 0.83 | SMN1; SMN2 (0.63) | ALDH1A1TSHRKDM4EPOLBLMNA | |
| SCHEMBL16028099 | 0.82 | PCSK9 (0.52) | ALDH1A1TSHRLMNATRPC5TRPC4 | |
| SCHEMBL16028970 | 0.82 | BRAF (0.56) | ALDH1A1TSHRKDM4EPOLBRAB9A | |
| SCHEMBL18833810 | 0.81 | TRPC5 (0.65) | ALDH1A1TSHRPOLBRAB9ALMNA | |
| SCHEMBL16076165 | 0.81 | TSHR (0.68) | ALDH1A1TSHRKDM4EPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208976-A1 | PROCESS FOR THE PREPARATION OF 7-(4-CHLOROBENZYL)-1-(3-HYDROXYPROPYL)-3-METHYL-8-(3-(TRIFLUOROMETHOXY)-PHENOXY)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208976-A1 | PROCESS FOR THE PREPARATION OF 7-(4-CHLOROBENZYL)-1-(3-HYDROXYPROPYL)-3-METHYL-8-(3-(TRIFLUOROMETHOXY)-PHENOXY)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | DPYD, P2RX7, DHPS | ALDH1A1 497/4885TSHR 3827/4885KDM4E 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.