Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248037 | 0.88 | SIRT6 (0.62) | SIRT6MAPTALDH1A1POLBLMNA | |
| SCHEMBL15271381 | 0.79 | SIRT6 (0.81) | SIRT6MAPTALDH1A1POLBLMNA | |
| SCHEMBL6151230 | 0.79 | SIRT6 (0.81) | SIRT6MAPTALDH1A1POLBLMNA | |
| SCHEMBL1045292 | 0.78 | SIRT6 (0.69) | SIRT6MAPTALDH1A1POLBLMNA | |
| SCHEMBL8828657 | 0.77 | ALDH1A1 (0.49) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL27409046 | 0.77 | DRD2 (0.42) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL374222 | 0.77 | SIRT6 (0.68) | SIRT6MAPTALDH1A1POLBLMNA | |
| SCHEMBL27413682 | 0.77 | DRD2 (0.56) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL6945690 | 0.75 | SIRT6 (0.65) | SIRT6MAPTALDH1A1POLBLMNA | |
| SCHEMBL4822106 | 0.75 | SIRT6 (0.60) | SIRT6MAPTALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1074766-C | Alkylaminobenzothiazole and -benzoxazole derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2001-11-14 | — | — | CN | disclosed |
| CN-1218461-A | Alkylaminobenzothiazole and -benzoxazole derivatives | JANSSEN PHARMACEUTICA NV (NL) | 1999-06-02 | — | — | CN | disclosed |