Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340569 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL27409046 | 0.83 | DRD2 (0.42) | ALDH1A1MAPTGFERKDM4EKMT2A | |
| SCHEMBL27413682 | 0.83 | DRD2 (0.56) | ALDH1A1MAPTLMNAMAPK1GFER | |
| SCHEMBL27412409 | 0.77 | SIRT6 (0.59) | ALDH1A1MAPTLMNAHTTMEN1 | |
| SCHEMBL8981809 | 0.77 | MAPT (0.57) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL8828413 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL10373626 | 0.75 | MAPT (0.77) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL27536578 | 0.74 | DRD2 (0.43) | MAPTMAPK1KDM4EDRD4CYP2C19 | |
| SCHEMBL8828393 | 0.74 | HSD17B10 (0.55) | ALDH1A1MAPTLMNATDP1KDM4E | |
| SCHEMBL8828418 | 0.74 | DRD2 (0.47) | ALDH1A1MAPK1GFERKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |