Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997087 | 0.86 | SLC1A5 (0.48) | KIF11SLC1A5GRIK1GRIK2SLC1A1 | |
| SCHEMBL9925277 | 0.86 | SLC1A5 (0.48) | KIF11SLC1A5GRIK1GRIK2SLC1A1 | |
| SCHEMBL6098839 | 0.81 | TDP1 (0.57) | TDP1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9301762 | 0.77 | SLC1A5 (0.49) | KIF11TDP1SLC1A5NPC1RAB9A | |
| Water SCHEMBL28445354 | 0.76 | KMT2A (0.58) | TDP1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL8995839 | 0.76 | TDP1 (0.52) | TDP1CYP1A2NPC1RAB9AKMT2A | |
| SCHEMBL5084403 | 0.76 | ALDH1A1 (0.44) | TDP1SLC1A5KMT2AL3MBTL1LTA4H | |
| SCHEMBL5084405 | 0.76 | ALDH1A1 (0.44) | TDP1SLC1A5KMT2AL3MBTL1LTA4H | |
| SCHEMBL28365251 | 0.75 | TDP1 (0.47) | TDP1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL5078447 | 0.75 | LMNA (0.46) | SLC1A5CYP1A2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1394857-A | Compound used as antiproliferative agent and glycinamide ribonucleotide transformylase inhibitor | AQOURON PHARMACEUTICALS INC (US) | 2003-02-05 | — | — | CN | disclosed |
| CN-1091770-C | Compounds useful as antiproliferative agents and GARFT inhibitors | AGOURON PHARAMCEUTICALS INC (US) | 2002-10-02 | — | — | CN | disclosed |
| CN-1154110-A | Compounds useful as antiproliferative agents and GARFT inhibitors | AGOURON PHARMA (US) | 1997-07-09 | — | — | CN | disclosed |