SCHEMBL9301762

SCHEMBL9301762

Cc1ccc(COC(=O)CC[C@H](N)C(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 1/20 0.49
LMNA P02545 2/20 0.49
ALDH1A1 P00352 4/20 0.48
MAPT P10636 2/20 0.47
GAA P10253 1/20 0.47
KIF11 P52732 4/20 0.46
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 2/20 0.44
LTA4H P09960 2/20 0.42
SLC15A1 P46059 1/20 0.42
NPY1R P25929 1/20 0.41
MAOB P27338 1/20 0.41
ADORA2A P29274 1/20 0.41
RECQL P46063 1/20 0.41
NPY2R P49146 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC7A5 Q01650 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124385 0.86 SLC15A1 (0.55) ALDH1A1KMT2ALTA4HSLC15A1TDP1
SCHEMBL4850398 0.86 SLC15A1 (0.55) ALDH1A1KMT2ALTA4HSLC15A1TDP1
SCHEMBL432780 0.86 SLC15A1 (0.55) ALDH1A1KMT2ALTA4HSLC15A1TDP1
SCHEMBL8191972 0.86 KIF11 (0.50) SLC1A5ALDH1A1KIF11KMT2ALTA4H
SCHEMBL17821267 0.85 LMNA (0.60) SLC1A5LMNAALDH1A1MAPTGAA
Hydrochloric Acid SCHEMBL29398213 0.85 SLC15A1 (0.53) ALDH1A1KMT2ALTA4HSLC15A1TDP1
SCHEMBL11488431 0.85 LTA4H (0.48) MAPTKMT2ALTA4HSLC15A1
Alanine SCHEMBL4410297 0.84 SLC15A1 (0.52) LMNAALDH1A1KMT2ALTA4HSLC15A1
Urea SCHEMBL4473115 0.84 SLC15A1 (0.52) ALDH1A1KMT2ALTA4HSLC15A1L3MBTL1
Glutamic Acid SCHEMBL7243656 0.82 SLC1A1 (0.53) ALDH1A1LTA4HSLC15A1L3MBTL1SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10030103-B2 Stable helical ionic polypeptides THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-07-24 US disclosed
EP-0605484-A1 PEPTIDES HAVING GROWTH HORMONE RELEASING ACTIVITY THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) 1994-07-13 EP disclosed
WO-1993004081-A1 PEPTIDES HAVING GROWTH HORMONE RELEASING ACTIVITY ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 1993-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10030103-B2 Stable helical ionic polypeptides GHITM, SLC7A1, PICALM SLC1A5 6/4885LMNA 2898/4885ALDH1A1 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.