SCHEMBL27412940

SCHEMBL27412940

CC(=O)NN1CCCCC1.c1cc2cc-2c1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.49
CNR2 P34972 6/20 0.46
POLB P06746 2/20 0.45
LMNA P02545 1/20 0.45
CNR1 P21554 4/20 0.44
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
GLA P06280 1/20 0.41
CYP3A4 P08684 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
ALOX12 P18054 1/20 0.41
NFKB1 P19838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8033657 0.85 HTT (0.50) HTTCNR2POLBLMNACNR1
SCHEMBL6123494 0.81 HTT (0.45) HTTPOLBLMNAKDM4EALDH1A1
SCHEMBL637498 0.81 HTT (0.45) HTTPOLBLMNAKDM4EALDH1A1
SCHEMBL715894 0.79
SCHEMBL11350868 0.78 HTT (0.40) HTTCNR2POLBLMNAKDM4E
SCHEMBL19052251 0.74
SCHEMBL4827396 0.73 GAA (0.43) POLBKDM4EALDH1A1CYP3A4GAA
SCHEMBL10545379 0.73 MEN1 (0.40) POLBKDM4EALDH1A1GAA
SCHEMBL29107984 0.72 CA2 (0.41) HTTLMNAKDM4EALDH1A1TP53
SCHEMBL4612423 0.71 HTT (0.77) HTTCNR2POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100400039-C Composition for treating tumor diseases and application thereof BURZYNSKI STANISLAW R (US) 2008-07-09 CN disclosed
CN-1660061-A Composition for treating tumor diseases and application thereof BURZYNSKI STANISLAW R (US) 2005-08-31 CN disclosed
CN-1605334-A Use of composition in preparing medicine for treating tumor diseases BURZYNSKI STANISLAW R (US) 2005-04-13 CN disclosed
CN-1191064-C Pharmaceutical composition containing phenylacetylglutamine, phenylacetylisoglutamine and/or derivatives thereof BURZYNSKI STANISLAW R (US) 2005-03-02 CN disclosed
CN-1090970-C Process for preparing uropoly acid-peptide composition YONGSHENG PHARMACEUTICAL CO LT (CN) 2002-09-18 CN disclosed
CN-1090971-C Uropoly acid-peptide composition YONGSHENG PHARMACEUTICAL CO LT (CN) 2002-09-18 CN disclosed
CN-1088597-C Uropoly aic-peptide composition and its usage YONGSHENG PHARMACEUTICAL CO LT (CN) 2002-08-07 CN disclosed
CN-1319010-A Therapeutic methods for administering phenylacetylglutamine, phenylacetylisoglutamine, and/or phenylacetate BURZYNSKI STANISLAW R (US) 2001-10-24 CN disclosed
CN-1293959-A Uropoly aic-peptide composition and its usage YONGSHENG PHARMACEUTICAL CO LT (CN) 2001-05-09 CN disclosed
CN-1294000-A Process for preparing uropoly acid-peptide composition YONGSHENG PHAMACEUTICAL CO LTD (CN) 2001-05-09 CN disclosed
CN-1294001-A Uropoly acid-peptide composition YONGSHENG PHARMACEUTICAL CO LT (CN) 2001-05-09 CN disclosed