Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275381 | 0.70 | ALDH1A1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL25702894 | 0.67 | MOGAT2 (0.32) | — | |
| SCHEMBL27412704 | 0.66 | HDAC6 (0.42) | JAK2JAK3PSEN1PSEN2APH1B | |
| SCHEMBL8057713 | 0.65 | PSEN1 (0.44) | JAK2JAK3PSEN1PSEN2APH1B | |
| SCHEMBL17723351 | 0.64 | PSEN1 (0.43) | JAK2JAK3PSEN1PSEN2APH1B | |
| SCHEMBL5910308 | 0.60 | MEN1 (0.45) | HDAC6MEN1KMT2AFAAHCYP2D6 | |
| SCHEMBL27745176 | 0.60 | MEN1 (0.45) | HDAC6MEN1KMT2AFAAHCYP2D6 | |
| SCHEMBL22473565 | 0.60 | MEN1 (0.45) | HDAC6MEN1KMT2AFAAHCYP2D6 | |
| SCHEMBL27745218 | 0.60 | MEN1 (0.45) | HDAC6MEN1KMT2AFAAHCYP2D6 | |
| SCHEMBL18355944 | 0.59 | MEN1 (0.42) | HDAC6MEN1KMT2AFAAHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137968-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | CAPULUS THERAPEUTICS, LLC (US) | 2024-06-27 | — | — | WO | disclosed |