Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27412703 | 0.85 | MET (0.44) | HDAC6METPIM1CYP1A2 | |
| SCHEMBL31275381 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MEN1POLBGAAKMT2A | |
| SCHEMBL27413299 | 0.77 | MET (0.43) | METPIM1CYP1A2MAPK14 | |
| SCHEMBL27412690 | 0.72 | MET (0.42) | HDAC6METPSEN1PSEN2APH1B | |
| SCHEMBL27412509 | 0.72 | LMNA (0.43) | ALDH1A1GAAHSD17B10ALOX15HTT | |
| SCHEMBL8057713 | 0.70 | PSEN1 (0.44) | HDAC6ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL27412529 | 0.69 | ALDH1A1 (0.50) | ALDH1A1GAAPIM1HSD17B10HTT | |
| SCHEMBL17723351 | 0.69 | PSEN1 (0.43) | HDAC6MEN1KMT2AJAK2JAK3 | |
| SCHEMBL27412754 | 0.67 | GPR55 (0.44) | ALDH1A1GAAPIM1MAPK14 | |
| SCHEMBL27413402 | 0.66 | JAK2 (0.38) | HDAC6MEN1KMT2AJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137968-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | CAPULUS THERAPEUTICS, LLC (US) | 2024-06-27 | — | — | WO | disclosed |