Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5910308 | 1.00 | MEN1 (0.45) | MEN1KMT2AFAAHSLC6A9HDAC6 | |
| SCHEMBL27745218 | 1.00 | MEN1 (0.45) | MEN1KMT2AFAAHSLC6A9HDAC6 | |
| Propane SCHEMBL7390979 | 0.98 | MEN1 (0.44) | MEN1KMT2AFAAHSLC6A9HDAC6 | |
| SCHEMBL22473565 | 0.83 | MEN1 (0.45) | MEN1KMT2AFAAHSLC6A9HDAC6 | |
| SCHEMBL6646740 | 0.81 | TRPA1 (0.41) | MEN1KMT2AFAAHHDAC6TAAR1 | |
| SCHEMBL8284242 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2ATDP1CYP2D6LMNA | |
| SCHEMBL8285914 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2ATDP1CYP2D6LMNA | |
| SCHEMBL8285019 | 0.80 | ALPL (0.44) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8285925 | 0.80 | ALPL (0.44) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14452548 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2ATDP1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101460446-B | Method for producing optically active 1-(fluoro-,trifluoromethyl-or trifluoromethoxy-substituted phenyl)alkylamine n-monoalkyl derivative | CENTRAL GLASS CO LTD | 2013-04-24 | — | — | CN | disclosed |
| CN-101460446-A | Method for producing optically active 1-(fluoro-,trifluoromethyl-or trifluoromethoxy-substituted phenyl)alkylamine n-monoalkyl derivative | CENTRAL GLASS CO LTD (JP) | 2009-06-17 | — | — | CN | disclosed |