Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479969 | 0.91 | MAPT (0.35) | KDM4EALDH1A1MEN1KMT2ATLR7 | |
| SCHEMBL27391542 | 0.91 | TLR7 (0.35) | KDM4EALDH1A1TLR7LMNA | |
| SCHEMBL27534349 | 0.90 | P2RX3 (0.32) | MEN1KMT2ALMNAPIM1PIM3 | |
| SCHEMBL27534451 | 0.90 | PIM1 (0.33) | MEN1KMT2APIM1PIM3ENPP2 | |
| SCHEMBL27389892 | 0.89 | ENPP2 (0.32) | MEN1KMT2APIM1PIM3ENPP2 | |
| SCHEMBL27479972 | 0.87 | TLR7 (0.35) | MEN1KMT2ATLR7PPARGP2RX7 | |
| SCHEMBL27394335 | 0.87 | MEN1 (0.34) | KDM4EALDH1A1MEN1KMT2ATLR7 | |
| SCHEMBL27413610 | 0.87 | PLA2G2A (0.34) | KDM4EALDH1A1MEN1KMT2ATLR7 | |
| SCHEMBL27534463 | 0.86 | GNRHR (0.36) | KDM4EALDH1A1TLR7LMNAPLA2G10 | |
| SCHEMBL27421127 | 0.85 | MAPT (0.34) | ALDH1A1MEN1KMT2ATLR7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093535-C | Imidazole derivative | SHIONOGI & CO (JP) | 2002-10-30 | — | — | CN | disclosed |
| CN-1158609-A | Imidazole derivative | SHIONOGI & CO (JP) | 1997-09-03 | — | — | CN | disclosed |