Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27393446 | 0.91 | TLR7 (0.36) | PLA2G2ATLR7CA12CA1CA2 | |
| SCHEMBL27390720 | 0.91 | S1PR3 (0.36) | PLA2G2AALDH1A1TP53SLC16A3SLC16A1 | |
| SCHEMBL27537386 | 0.91 | ADRA1D (0.34) | PLA2G2ATLR7 | |
| SCHEMBL27534445 | 0.91 | S1PR3 (0.37) | PLA2G2ATLR7ALDH1A1MEN1KMT2A | |
| SCHEMBL27407857 | 0.87 | TLR7 (0.36) | PLA2G2ATLR7CA12CA1CA2 | |
| SCHEMBL27389957 | 0.87 | ALDH1A1 (0.35) | TLR7CA12CA1CA2CA9 | |
| SCHEMBL27413615 | 0.87 | KDM4E (0.33) | PLA2G2ATLR7KDM4EALDH1A1MEN1 | |
| SCHEMBL27414207 | 0.85 | LOXL2 (0.35) | PLA2G2ATLR7CA12CA1CA2 | |
| SCHEMBL27412966 | 0.85 | ENPP2 (0.36) | PLA2G2AKDM4EALDH1A1HTTATM | |
| SCHEMBL27391542 | 0.84 | TLR7 (0.35) | TLR7KDM4EALDH1A1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093535-C | Imidazole derivative | SHIONOGI & CO (JP) | 2002-10-30 | — | — | CN | disclosed |
| CN-1158609-A | Imidazole derivative | SHIONOGI & CO (JP) | 1997-09-03 | — | — | CN | disclosed |