Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27409224 | 0.83 | KIF11 (0.44) | KIF11RAB9APTGESCYP2C9MAPT | |
| SCHEMBL27532886 | 0.81 | KIF11 (0.50) | KIF11RAB9APTGESCYP2C9MAPT | |
| SCHEMBL27410225 | 0.78 | DAO (0.49) | KIF11RAB9APTGESCYP2C9MAPT | |
| SCHEMBL27388577 | 0.77 | PTGS2 (0.53) | KIF11RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL9312351 | 0.75 | DAO (0.44) | KIF11RAB9APTGESCYP2C9MAPT | |
| SCHEMBL9566941 | 0.74 | KIF11 (0.42) | KIF11RAB9APTGESCYP2C9POLB | |
| SCHEMBL27420343 | 0.74 | KDM4E (0.46) | KIF11RAB9APTGESCYP2C9MAPT | |
| SCHEMBL27411716 | 0.74 | KIF11 (0.43) | KIF11RAB9APTGESCYP2C9MAPT | |
| SCHEMBL9308464 | 0.74 | KDM4E (0.45) | KIF11RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL27532885 | 0.74 | PDE9A (0.49) | KIF11RAB9AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1077192-A | The 2-oxoquinoline derivatives | MERCK PATENT GMBH (DE) | 1993-10-13 | — | — | CN | disclosed |