Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566925 | 0.89 | PDE3B (0.45) | KIF11RAB9ATSHRPDE3BPDE3A | |
| SCHEMBL9566894 | 0.81 | KIF11 (0.43) | KIF11RAB9ATSHRKDM4EALDH1A1 | |
| SCHEMBL27388577 | 0.78 | PTGS2 (0.53) | KIF11RAB9ATSHRKDM4EALDH1A1 | |
| SCHEMBL27532886 | 0.78 | KIF11 (0.50) | KIF11RAB9ATSHRPDE3BPDE3A | |
| SCHEMBL27410225 | 0.77 | DAO (0.49) | KIF11RAB9ATSHRKDM4EALDH1A1 | |
| SCHEMBL9312351 | 0.76 | DAO (0.44) | KIF11RAB9ATSHRKDM4EDAO | |
| SCHEMBL27420343 | 0.76 | KDM4E (0.46) | KIF11POLBRAB9ATSHRKDM4E | |
| SCHEMBL27413181 | 0.76 | DAO (0.48) | KIF11KDM4EDAOCYP2C9PTGES | |
| SCHEMBL27532885 | 0.75 | PDE9A (0.49) | KIF11RAB9ATSHRKDM4EALDH1A1 | |
| SCHEMBL9309057 | 0.75 | PARP1 (0.48) | KIF11KDM4EALDH1A1DAOPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561252-A1 | 2-Oxoquinoline derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |