Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | DRD1 | P21728 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD5 | P21918 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033288 | 0.79 | HPGD (0.49) | HPGDSMN1; SMN2DRD2HTR1ATSHR | |
| SCHEMBL7756044 | 0.77 | HTR1A (0.41) | DRD2HTR1ATSHRL3MBTL1FOLH1 | |
| Ethylene SCHEMBL28237007 | 0.76 | HPGD (0.46) | HPGDSMN1; SMN2DRD2HTR1ATSHR | |
| SCHEMBL27413842 | 0.74 | LTA4H (0.46) | TSHRLTA4HL3MBTL1 | |
| SCHEMBL7591220 | 0.73 | HTR1A (0.71) | HPGDDRD2HTR1ATSHRTP53 | |
| SCHEMBL246372 | 0.73 | HPGD (0.58) | HPGDSMN1; SMN2DRD2TSHRHRH1 | |
| SCHEMBL27332065 | 0.73 | IDO1 (0.45) | HPGDSMN1; SMN2CYP3A4ALDH1A1 | |
| Oxirane SCHEMBL28878523 | 0.72 | DRD1 (0.48) | HPGDSMN1; SMN2DRD2TSHRHRH1 | |
| SCHEMBL5653059 | 0.72 | ABCB1 (0.59) | SMN1; SMN2DRD2HTR1AL3MBTL1LMNA | |
| SCHEMBL4003505 | 0.72 | KEAP1 (0.59) | HPGDTSHRLTA4HCYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1100032-C | 3,4-disubstituted phenylethanolaminotetra lincarboxamide derivatives | KISSEI PHARMACEUTICAL (JP) | 2003-01-29 | — | — | CN | disclosed |
| CN-1216526-A | 3,4-disubstituted phenylethanolaminotetra lincarboxamide derivatives | KISSEI PHARMACEUTICAL (JP) | 1999-05-12 | — | — | CN | disclosed |