Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27418631 | 0.89 | NAAA (0.30) | — | |
| SCHEMBL5134484 | 0.80 | PTGS2 (0.48) | PTGS2NR4A2 | |
| SCHEMBL27415767 | 0.76 | PTGS2 (0.33) | PTGS2NR4A2MEN1NPC1RAB9A | |
| SCHEMBL5134825 | 0.70 | EGFR (0.43) | PTGS2NR4A2 | |
| SCHEMBL27418630 | 0.68 | CACNA1B (0.32) | — | |
| SCHEMBL27446301 | 0.68 | CYP2C9 (0.40) | PTGS2NR4A2MEN1KMT2A | |
| SCHEMBL16046136 | 0.67 | MAPT (0.41) | MEN1RAB9AKMT2A | |
| SCHEMBL6376816 | 0.67 | PTGS2 (0.45) | PTGS2 | |
| SCHEMBL14168700 | 0.65 | MMP2 (0.34) | — | |
| SCHEMBL5327141 | 0.62 | GAA (0.31) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098256-C | Substd. benzenesulfonamide derivs as prodrugs of COX-2 inhibitors | SEARLE & CO (US) | 2003-01-08 | — | — | CN | claimed |
| CN-1216043-A | Substd. benzenesulfonamide derivs as prodrugs of COX-2 inhibitors | SEARLE & CO (US) | 1999-05-05 | — | — | CN | claimed |
| CN-1098256-C | Substd. benzenesulfonamide derivs as prodrugs of COX-2 inhibitors | SEARLE & CO (US) | 2003-01-08 | — | — | CN | disclosed |
| CN-1216043-A | Substd. benzenesulfonamide derivs as prodrugs of COX-2 inhibitors | SEARLE & CO (US) | 1999-05-05 | — | — | CN | disclosed |