Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TGM2 | P21980 | 1/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546647 | 0.90 | LMNA (0.71) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL18254066 | 0.90 | HTT (0.81) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL15346534 | 0.88 | HTT (0.79) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL9874334 | 0.88 | HTT (0.79) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL9340146 | 0.88 | HTT (0.79) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL13055383 | 0.86 | LMNA (0.80) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL535583 | 0.85 | HTT (0.74) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL8395285 | 0.85 | HTT (0.74) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL2402780 | 0.85 | HTT (0.74) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL13895513 | 0.85 | HTT (0.74) | HTTLMNASMN1; SMN2TGM2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252939-B2 | Sulfoximinamide compounds for combating animal pests | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8252939-B2 | Sulfoximinamide compounds for combating animal pests | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| EP-2307370-B1 | SULFOXIMINAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2012-01-04 | — | — | EP | disclosed |
| US-20110306493-A1 | Sulfoximinamide Compounds for Combating Animal Pests | BASF SE (DE) | 2011-12-15 | — | — | US | disclosed |
| US-20110306493-A1 | Sulfoximinamide Compounds for Combating Animal Pests | BASF SE (DE) | 2011-12-15 | — | — | US | disclosed |
| WO-2011069955-A1 | SULFONIMIDAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-06-16 | — | — | WO | disclosed |
| WO-2009156336-A1 | SULFOXIMINAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2009-12-30 | — | — | WO | disclosed |
| EP-0094815-B1 | OLIGOPEPTIDE PRODRUGS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4479898-A | Oligopeptide prodrugs | SMITHKLINE BECKMAN CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4454065-A | INCREASE CELL MEMBRANE PERMEABILITY | SMITHKLINE BECKMAN CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| EP-0094815-A2 | Oligopeptide prodrugs | SMITHKLINE BECKMAN CORPORATION (US) | 1983-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306493-A1 | Sulfoximinamide Compounds for Combating Animal Pests | PRDX1, PRDX2, PRDX4 | HTT 354/4885LMNA 4716/4885SMN1; SMN2 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.