SCHEMBL535583

SCHEMBL535583

O=C(NCCCO)OCc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.74
LMNA P02545 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
TGM2 P21980 1/20 0.65
KEAP1 Q14145 2/20 0.63
NFE2L2 Q16236 2/20 0.63
L3MBTL1 Q9Y468 2/20 0.56
MAPT P10636 1/20 0.55
FOLH1 Q04609 3/20 0.54
SLC1A3 P43003 1/20 0.53
SLC1A1 P43005 1/20 0.53
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
DPP8 Q6V1X1 1/20 0.52
DPP7 Q9UHL4 1/20 0.52
SLC6A2 P23975 1/20 0.51
SLC6A3 Q01959 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL5116842 0.98 HTT (0.72) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL667447 0.95 HTT (0.72) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL9766289 0.94 HTT (0.67) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL8371424 0.94 HTT (0.67) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL234271 0.94 HTT (0.70) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL17634037 0.94 HTT (0.70) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL16692078 0.94 HTT (0.70) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL887187 0.94 HTT (0.70) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL31400174 0.94 HTT (0.70) HTTLMNASMN1; SMN2TGM2KEAP1
SCHEMBL11441576 0.94 HTT (0.70) HTTLMNASMN1; SMN2TGM2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101668-B Mutant enzyme, fermentation production method thereof and application of mutant enzyme in preparation of buckwheat alkali 华南师范大学 2025-05-09 CN claimed
CN-119101668-A Mutant enzyme, fermentation production method thereof and application of mutant enzyme in preparation of buckwheat alkali 华南师范大学 2024-12-10 CN claimed
CN-103214399-A Preparation method of N-carbobenzoxy-3-amino propionaldehyde UNIV EAST CHINA NORMAL 2013-07-24 CN claimed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
US-20260049317-A1 GalNAc Compound Containing Triazole Structure and Oligonucleotide Conjugate Thereof BEIJING YOUCARE KECHUANG PHARMACEUTICAL TECH CO LTD (CN) 2026-02-19 US disclosed
EP-4696327-A1 GALNAC COMPOUND CONTAINING TRIAZOLE STRUCTURE AND OLIGONUCLEOTIDE CONJUGATE THEREOF Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd. (CN) 2026-02-18 EP disclosed
US-20260041686-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS GLAXOSMITHKLINE IP DEV LTD (GB) 2026-02-12 US disclosed
US-12521393-B2 Cytotoxicity targeting chimeras for CCR2-expressing cells GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2026-01-13 US disclosed
EP-4640280-A2 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS GlaxoSmithKline Intellectual Property Development Limited (GB) 2025-10-29 EP disclosed
EP-4384223-B1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS GLAXOSMITHKLINE IP DEV LTD (GB) 2025-10-01 EP disclosed
WO-1995013817-A1 ENDOTHELIN CONVERTING ENZYME INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1995-05-26 WO disclosed
EP-0639586-A1 Phosphonic acid derivatives, process for their preparation and pharmaceutical compositions comprising them ADIR ET COMPAGNIE (FR) 1995-02-22 EP disclosed
EP-0535967-A2 Cyclohexapeptidyl bisamine compounds MERCK & CO. INC. (US) 1993-04-07 EP disclosed
US-5064819-A Antidepressants, anxiolytic agents, GABA antagonists CIBA-GEIGY CORPORATION (US) 1991-11-12 US disclosed
WO-1991002741-A1 SUGAR ALCOHOL DERIVATIVES, A PROCESS FOR PREPARING 3-DEOXY-2-OCTULOSONIC ACID AND 3-DEOXY-2-HEPTULOSONIC ACID COMPOUNDS AND DERIVATIVES RIJKSUNIVERSITEIT TE LEIDEN (NL) 1991-03-07 WO disclosed
US-4954519-A Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents GEORGIA TECH RESEARCH CORPORATION (US) 1990-09-04 US disclosed
US-4845242-A ANTITUMOR GEORGIA TECH RESEARCH CORPORATION (US) 1989-07-04 US disclosed
US-4610983-A N-acyl acidic amino acid diamide derivative, a salt thereof, and an anti-ulcer agent containing the same TOYAMA CHEMICAL CO., LTD. (JP) 1986-09-09 US disclosed
US-4180565-A ANTIBACTERIAL AGENTS, ANTIBIOTICS SCHERING CORPORATION (US) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049317-A1 GalNAc Compound Containing Triazole Structure and Oligonucleotide Conjugate Thereof CSGALNACT1, B3GAT3, SLC10A1 HTT 3613/4885LMNA 995/4885SMN1; SMN2 2509/4885
US-20260041686-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS CCR2, CCR1, CCRL2 HTT 2256/4885LMNA 4546/4885SMN1; SMN2 1993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.