SCHEMBL27419952

SCHEMBL27419952

Bc1c(N)cccc1COCC

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 1/20 0.33
CYP3A4 P08684 2/20 0.32
TSHR P16473 1/20 0.32
PIK3CA P42336 1/20 0.32
ADRA1A P35348 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7689047 0.80 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP3A4CYP1A2CYP2C9
SCHEMBL30844600 0.78 GABRA1 (0.42) ALDH1A1HSD17B10CYP3A4TSHRPIK3CA
SCHEMBL25084418 0.78 GABRA1 (0.42) ALDH1A1HSD17B10CYP3A4TSHRPIK3CA
SCHEMBL18184985 0.74 GABRA1 (0.38) ALDH1A1HSD17B10CYP3A4TSHRPIK3CA
SCHEMBL648250 0.73 IDO1 (0.39) ALDH1A1TSHRADRA1A
SCHEMBL25086044 0.72
SCHEMBL27419955 0.71 TRPV4 (0.33) ALDH1A1HSD17B10CYP3A4TP53
SCHEMBL4964134 0.71 ADRA1A (0.36) ALDH1A1HSD17B10CYP3A4ADRA1ATP53
SCHEMBL6418440 0.71 ADRA1A (0.36) ALDH1A1HSD17B10CYP3A4TSHRADRA1A
SCHEMBL15771305 0.70 IDO1 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393920-A1 AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2024-07-03 EP disclosed