Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15132934 | 0.81 | MAOB (0.59) | MAOBNPC1RAB9ASCN9A | |
| SCHEMBL13450401 | 0.78 | MAOB (0.60) | HDAC1HDAC6HDAC5MAOBFFAR1 | |
| SCHEMBL20665441 | 0.78 | IDO1 (0.39) | MAPTPTGS2 | |
| SCHEMBL27428301 | 0.77 | MME (0.40) | MAOBFFAR1ACACAMRGPRX4NPC1 | |
| SCHEMBL27358340 | 0.77 | IDO1 (0.38) | MAOBFFAR1ACACAPTGS2 | |
| SCHEMBL26581160 | 0.77 | MAOB (0.55) | MAOBMRGPRX4NPC1RAB9ASCN9A | |
| SCHEMBL17129304 | 0.76 | DGAT1 (0.40) | MAOBFFAR1ACACANPC1RAB9A | |
| SCHEMBL8102862 | 0.76 | NPC1 (0.56) | HDAC1HDAC6HDAC5MAOBNPC1 | |
| SCHEMBL15472336 | 0.75 | MAOB (0.49) | MAOBACACANPC1RAB9ASCN9A | |
| SCHEMBL17644774 | 0.74 | MAOB (0.68) | MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | NR3C1, NR3C2, MC2R | HDAC1 1432/4885HDAC6 832/4885HDAC5 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.