Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27422020 | 0.86 | MEN1 (0.57) | MEN1KMT2AHSD17B1HSD17B2LMNA | |
| SCHEMBL3061861 | 0.81 | MEN1 (0.48) | MEN1KMT2AHSD17B1HSD17B2LMNA | |
| SCHEMBL3058830 | 0.79 | HSD17B1 (0.50) | MEN1KMT2AHSD17B1HSD17B2LMNA | |
| SCHEMBL3047557 | 0.78 | KMO (0.52) | MEN1KMT2AHSD17B1HSD17B2S1PR1 | |
| SCHEMBL13139532 | 0.76 | MEN1 (0.47) | MEN1KMT2AHSD17B1HSD17B2LMNA | |
| SCHEMBL13139523 | 0.75 | MEN1 (0.46) | MEN1KMT2AHSD17B1HSD17B2LMNA | |
| SCHEMBL27422029 | 0.71 | MEN1 (0.56) | MEN1KMT2AHSD17B1HSD17B2LMNA | |
| SCHEMBL14433794 | 0.70 | THRB (0.70) | MEN1KMT2AHSD17B1HSD17B2LMNA | |
| SCHEMBL27423760 | 0.70 | MEN1 (0.61) | MEN1KMT2AHSD17B1HSD17B2LMNA | |
| SCHEMBL14433960 | 0.69 | HSD17B1 (0.56) | MEN1KMT2AHSD17B1HSD17B2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137813-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |