Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524823 | 0.83 | ADORA2B (0.36) | EP300KAT2BADORA2BDRD2 | |
| SCHEMBL27342675 | 0.70 | MAPT (0.48) | MAPTCYP11B2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27281889 | 0.70 | SMN1; SMN2 (0.44) | CYP3A4HTTMAPTCYP11B2ALDH1A1 | |
| SCHEMBL27333035 | 0.69 | CYP19A1 (0.47) | CYP2A6CYP3A4HTTCYP2E1EP300 | |
| SCHEMBL27338916 | 0.69 | CYP2A6 (0.44) | CYP2A6CYP3A4HTTCYP2E1ELANE | |
| SCHEMBL27523033 | 0.69 | CYP3A4 (0.44) | CYP2A6CYP3A4HTTCYP2E1ELANE | |
| SCHEMBL27333031 | 0.69 | HTT (0.44) | CYP2A6CYP3A4HTTCYP2E1ELANE | |
| SCHEMBL7835814 | 0.69 | DRD2 (0.61) | HTTCYP11B2DRD2DRD3 | |
| SCHEMBL27341439 | 0.68 | ALDH1A1 (0.50) | CYP2A6CYP3A4CYP2E1CYP11B2ALDH1A1 | |
| SCHEMBL27336690 | 0.68 | CYP2A6 (0.42) | CYP2A6CYP3A4HTTCYP2E1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043990-C | Imidazolidinone derivative, acid-addition salt therefor, and remedy for senile dementia | KYORIN SEIYAKU KK (JP) | 1999-07-07 | — | — | CN | disclosed |
| CN-1135215-A | Imidazolidinone derivative, acid-addition salt therefor, and remedy for senile dementia | KYORIN SEIYAKU KK (JP) | 1996-11-06 | — | — | CN | disclosed |